Lymphadenitis caused by Purpureocillium lilacinum in a patient with CARD9 deficiency

We hereby make the first report of a case of mycosis caused by Purpureocillium lilacinum in CARD9 deficiency. A 40-year-old woman complained of lymph node swellings in the left cervical area. She also had chronic mucocutaneous candidiasis (CMC), and was found to have CARD9 deficiency. Lymphadenitis...

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Autores principales: Majima, Hidetaka, Inoue, Yuzaburo, Otsuka, Yuichiro, Yaguchi, Takashi, Watanabe, Akira, Kamei, Katsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520493/
https://www.ncbi.nlm.nih.gov/pubmed/37767185
http://dx.doi.org/10.1016/j.mmcr.2023.100609
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author Majima, Hidetaka
Inoue, Yuzaburo
Otsuka, Yuichiro
Yaguchi, Takashi
Watanabe, Akira
Kamei, Katsuhiko
author_facet Majima, Hidetaka
Inoue, Yuzaburo
Otsuka, Yuichiro
Yaguchi, Takashi
Watanabe, Akira
Kamei, Katsuhiko
author_sort Majima, Hidetaka
collection PubMed
description We hereby make the first report of a case of mycosis caused by Purpureocillium lilacinum in CARD9 deficiency. A 40-year-old woman complained of lymph node swellings in the left cervical area. She also had chronic mucocutaneous candidiasis (CMC), and was found to have CARD9 deficiency. Lymphadenitis by P. lilacinum was confirmed. The diagnosis was difficult, as culturing the biopsy specimen at a cautiously selected temperature (25 °C) and genetic analysis were both required. Oral administration of voriconazole improved her lymphadenopathy.
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spelling pubmed-105204932023-09-27 Lymphadenitis caused by Purpureocillium lilacinum in a patient with CARD9 deficiency Majima, Hidetaka Inoue, Yuzaburo Otsuka, Yuichiro Yaguchi, Takashi Watanabe, Akira Kamei, Katsuhiko Med Mycol Case Rep Case Report We hereby make the first report of a case of mycosis caused by Purpureocillium lilacinum in CARD9 deficiency. A 40-year-old woman complained of lymph node swellings in the left cervical area. She also had chronic mucocutaneous candidiasis (CMC), and was found to have CARD9 deficiency. Lymphadenitis by P. lilacinum was confirmed. The diagnosis was difficult, as culturing the biopsy specimen at a cautiously selected temperature (25 °C) and genetic analysis were both required. Oral administration of voriconazole improved her lymphadenopathy. Elsevier 2023-09-18 /pmc/articles/PMC10520493/ /pubmed/37767185 http://dx.doi.org/10.1016/j.mmcr.2023.100609 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Majima, Hidetaka
Inoue, Yuzaburo
Otsuka, Yuichiro
Yaguchi, Takashi
Watanabe, Akira
Kamei, Katsuhiko
Lymphadenitis caused by Purpureocillium lilacinum in a patient with CARD9 deficiency
title Lymphadenitis caused by Purpureocillium lilacinum in a patient with CARD9 deficiency
title_full Lymphadenitis caused by Purpureocillium lilacinum in a patient with CARD9 deficiency
title_fullStr Lymphadenitis caused by Purpureocillium lilacinum in a patient with CARD9 deficiency
title_full_unstemmed Lymphadenitis caused by Purpureocillium lilacinum in a patient with CARD9 deficiency
title_short Lymphadenitis caused by Purpureocillium lilacinum in a patient with CARD9 deficiency
title_sort lymphadenitis caused by purpureocillium lilacinum in a patient with card9 deficiency
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520493/
https://www.ncbi.nlm.nih.gov/pubmed/37767185
http://dx.doi.org/10.1016/j.mmcr.2023.100609
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