Molecular characterization of a novel mitochondrial NOD-like receptor X1 in chicken that negatively regulates IFN-β expression via STING

NOD-like receptor X1 (NLRX1) is known for its unique mitochondrial localization and plays a negative role in innate immunity. The initial characterization and function of chicken NLRX1 remain unclear. Here, chicken mitochondrial-targeted NLRX1 (chNLRX1) protein was identified. It had relatively cons...

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Detalles Bibliográficos
Autores principales: Xu, Aiyun, Zhu, Xiang, Song, Tao, Zhang, Zhenyuan, Fei, Fei, Zhu, Qingxiao, Chang, Xinyue, Liu, Hongmei, Chen, Fangfang, Xu, Fazhi, Li, Lin, Liu, Xuelan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
IMMUNOLOGY, HEALTH AND DISEASE
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520534/
https://www.ncbi.nlm.nih.gov/pubmed/37741116
http://dx.doi.org/10.1016/j.psj.2023.103077

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