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Multimodal cartography of human lymphopoiesis reveals B and T/NK/ILC lineages are subjected to differential regulation

The developmental cartography of human lymphopoiesis remains incompletely understood. Here, we establish a multimodal map demonstrating that lymphoid specification follows independent direct or stepwise hierarchic routes converging toward the emergence of newly characterized CD117(lo) multi-lymphoid...

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Detalles Bibliográficos
Autores principales: Alhaj Hussen, Kutaiba, Chabaane, Emna, Nelson, Elisabeth, Lekiashvili, Shalva, Diop, Samuel, Keita, Seydou, Evrard, Bertrand, Lardenois, Aurélie, Delord, Marc, Verhoeyen, Els, Cornils, Kerstin, Kasraian, Zeinab, Macintyre, Elizabeth A., Cumano, Ana, Garrick, David, Goodhardt, Michele, Andrieu, Guillaume P., Asnafi, Vahid, Chalmel, Frederic, Canque, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520540/
https://www.ncbi.nlm.nih.gov/pubmed/37766969
http://dx.doi.org/10.1016/j.isci.2023.107890