Inaugurating High‐Throughput Profiling of Extracellular Vesicles for Earlier Ovarian Cancer Detection (Adv. Sci. 27/2023)

Early Cancer Message from the Source Most high‐grade serous ovarian cancers originate from the precursor lesions in the fallopian tube. This biological insight offers a novel opportunity to detect early ovarian cancer by assessing circulating extracellular vesicles specific to the fallopian tube. Bo...

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Detalles Bibliográficos
Autores principales: Jo, Ala, Green, Allen, Medina, Jamie E., Iyer, Sonia, Ohman, Anders W., McCarthy, Eric T., Reinhardt, Ferenc, Gerton, Thomas, Demehin, Daniel, Mishra, Ranjan, Kolin, David L., Zheng, Hui, Cheon, Jinwoo, Crum, Christopher P., Weinberg, Robert A., Rueda, Bo R., Castro, Cesar M., Dinulescu, Daniela M., Lee, Hakho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520619/
http://dx.doi.org/10.1002/advs.202370180
Descripción
Sumario:Early Cancer Message from the Source Most high‐grade serous ovarian cancers originate from the precursor lesions in the fallopian tube. This biological insight offers a novel opportunity to detect early ovarian cancer by assessing circulating extracellular vesicles specific to the fallopian tube. Both preclinical and pilot clinical studies demonstrate a promising perspective for such an approach. More details can be found in article number 2301930 by Cesar M. Castro, Daniela M. Dinulescu, Hakho Lee, and co‐workers. [Image: see text]

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