NLRP14 Safeguards Calcium Homeostasis via Regulating the K27 Ubiquitination of Nclx in Oocyte‐to‐Embryo Transition

Sperm‐induced Ca(2+) rise is critical for driving oocyte activation and subsequent embryonic development, but little is known about how lasting Ca(2+) oscillations are regulated. Here it is shown that NLRP14, a maternal effect factor, is essential for keeping Ca(2+) oscillations and early embryonic...

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Detalles Bibliográficos
Autores principales: Meng, Tie‐Gang, Guo, Jia‐Ni, Zhu, Liu, Yin, Yike, Wang, Feng, Han, Zhi‐Ming, Lei, Lei, Ma, Xue‐Shan, Xue, Yue, Yue, Wei, Nie, Xiao‐Qing, Zhao, Zheng‐Hui, Zhang, Hong‐Yong, Sun, Si‐Min, Ouyang, Ying‐Chun, Hou, Yi, Schatten, Heide, Ju, Zhenyu, Ou, Xiang‐Hong, Wang, Zhen‐Bo, Wong, Catherine C. L., Li, Zhonghan, Sun, Qing‐Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520637/
https://www.ncbi.nlm.nih.gov/pubmed/37493331
http://dx.doi.org/10.1002/advs.202301940

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