Cargando…

PUM1 Promotes Tumor Progression by Activating DEPTOR‐Meditated Glycolysis in Gastric Cancer

RNA‐binding proteins (RBPs) play essential roles in tumorigenesis and progression, but their functions in gastric cancer (GC) remain largely elusive. Here, it is reported that Pumilio 1 (PUM1), an RBP, induces metabolic reprogramming through post‐transcriptional regulation of DEP domain‐containing m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yin, Songcheng, Liu, Huifang, Zhou, Zhijun, Xu, Xiaoyu, Wang, Pengliang, Chen, Wei, Deng, Guofei, Wang, Han, Yu, Hong, Gu, Liang, Huo, Mingyu, Li, Min, Zeng, Leli, He, Yulong, Zhang, Changhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520643/ https://www.ncbi.nlm.nih.gov/pubmed/37469018 http://dx.doi.org/10.1002/advs.202301190

Ejemplares similares

Poor Prognosis and Therapeutic Responses in LILRB1-Expressing M2 Macrophages-Enriched Gastric Cancer Patients
por: Zhang, Yawei, et al.
Publicado: (2021)

Comprehensive analysis to construct a novel immune-related prognostic panel in aging-related gastric cancer based on the lncRNA‒miRNA-mRNA ceRNA network
por: Deng, Cuncan, et al.
Publicado: (2023)

El Pim-pam-pum
por: Ionesco, Eugène

The optimal strategy of multimodality therapies for resectable gastric cancer: evidence from a network meta-analysis
por: Yin, Songcheng, et al.
Publicado: (2019)

DEPTOR in Skeletal Development and Diseases
por: Perez-Tejeiro, Jose Miguel, et al.
Publicado: (2021)

PUmPER: phylogenies updated perpetually
por: Izquierdo-Carrasco, Fernando, et al.
Publicado: (2014)

APY0201 Represses Tumor Growth through Inhibiting Autophagy in Gastric Cancer Cells
por: Li, Huan, et al.
Publicado: (2022)

Elucidating the role of DEPTOR in Alzheimer’s disease
por: DAVIES, JULIE, et al.
Publicado: (2014)

Mammalian Pum1 and Pum2 Control Body Size via Translational Regulation of the Cell Cycle Inhibitor Cdkn1b
por: Lin, Kaibo, et al.
Publicado: (2019)

DEPTOR is a direct p53 target that suppresses cell growth and chemosensitivity
por: Cui, Danrui, et al.
Publicado: (2020)

Role of PUM RNA-Binding Proteins in Cancer
por: Smialek, Maciej J., et al.
Publicado: (2021)

Deptor: not only a mTOR inhibitor
por: Catena, Valeria, et al.
Publicado: (2017)

Regulation of human mTOR complexes by DEPTOR
por: Wälchli, Matthias, et al.
Publicado: (2021)

Function of Deptor and its roles in hematological malignancies
por: Morales-Martinez, Mario, et al.
Publicado: (2021)

SPHK1‐induced autophagy in peritoneal mesothelial cell enhances gastric cancer peritoneal dissemination
por: Yin, Songcheng, et al.
Publicado: (2019)

Risk Factors and Prognostic Impact of Postoperative Complications in Patients with Advanced Gastric Cancer Receiving Neoadjuvant Chemotherapy
por: Yu, Hong, et al.
Publicado: (2022)

Clinicopathological characteristics and prognosis of adolescents and young adults with gastric cancer after gastrectomy: a propensity score matching analysis
por: Chu, Hongwu, et al.
Publicado: (2023)

PUF-8, a C. elegans ortholog of the RNA-binding proteins PUM1 and PUM2, is required for robustness of the cell death fate
por: Xu, Jimei, et al.
Publicado: (2023)

Placental DEPTOR as a stress sensor during pregnancy
por: Mparmpakas, Dionisis, et al.
Publicado: (2011)

Loss of hepatic DEPTOR alters the metabolic transition to fasting
por: Caron, Alexandre, et al.
Publicado: (2017)

Construction of a hypoxia-immune-related prognostic panel based on integrated single-cell and bulk RNA sequencing analyses in gastric cancer
por: Deng, Cuncan, et al.
Publicado: (2023)

Characterization of RNP Networks of PUM1 and PUM2 Post-Transcriptional Regulators in TCam-2 Cells, a Human Male Germ Cell Model
por: Smialek, Maciej J., et al.
Publicado: (2020)

Stabilization of DEPTOR sensitizes hypopharyngeal cancer to radiotherapy via targeting degradation
por: Wang, Xuecen, et al.
Publicado: (2022)

Morphotype-specific effector functions of Cryptococcus neoformans PUM1
por: Kaur, Jan Naseer, et al.
Publicado: (2016)

PUM1 mediates the posttranscriptional regulation of human fetal hemoglobin
por: Elagooz, Reem, et al.
Publicado: (2022)

Calibration Method of Orthogonally Splitting Imaging Pose Sensor Based on KDFcmPUM
por: Zhao, Na, et al.
Publicado: (2019)

Meditation Quality Matters: Effects of Loving-Kindness and Compassion Meditations on Subjective Well-being are Associated with Meditation Quality
por: Zeng, Xianglong, et al.
Publicado: (2022)

Regulatory role of DEPTOR-mediated cellular autophagy and mitochondrial reactive oxygen species in angiogenesis in multiple myeloma
por: Wang, Jizhen, et al.
Publicado: (2021)

Comprehensive Identification of the Pum Gene Family and Its Involvement in Kernel Development in Maize
por: Feng, Wenqi, et al.
Publicado: (2023)

Antagonistic and cooperative AGO2-PUM interactions in regulating mRNAs
por: Sternburg, Erin L., et al.
Publicado: (2018)

PUM1 Is Overexpressed in Colon Cancer Cells With Acquired Resistance to Cetuximab
por: Liu, Qizhi, et al.
Publicado: (2021)

GALNT1 Enhances Malignant Phenotype of Gastric Cancer via Modulating CD44 Glycosylation to Activate the Wnt/β-catenin Signaling Pathway
por: Zhang, Junchang, et al.
Publicado: (2022)

DEPTOR stabilizes ErbB2 to promote the proliferation and survival of ErbB2-positive breast cancer cells
por: Bi, Yanli, et al.
Publicado: (2021)

DEPTOR has growth suppression activity against pancreatic cancer cells
por: Li, Hua, et al.
Publicado: (2014)

Deptor transcriptionally regulates endoplasmic reticulum homeostasis in multiple myeloma cells
por: Catena, Valeria, et al.
Publicado: (2016)

Palliative gastrectomy plus chemotherapy versus chemotherapy alone for incurable advanced gastric cancer: a meta-analysis
por: Wu, Pei, et al.
Publicado: (2018)

High DEPTOR expression correlates with poor prognosis in patients with esophageal squamous cell carcinoma
por: Liu, Nan-bo, et al.
Publicado: (2015)

SUMOylation of PUM2 promotes the vasculogenic mimicry of glioma cells via regulating CEBPD
por: Wang, Di, et al.
Publicado: (2020)

CircPUM1 promotes hepatocellular carcinoma progression through the miR‐1208/MAP3K2 axis
por: Zhang, Yaqiong, et al.
Publicado: (2020)

Loss of DEPTOR in renal tubules protects against cisplatin-induced acute kidney injury
por: Wang, Caixia, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_5uofqle3m2qnp9fqmvbt3v5e08