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HSP90β Impedes STUB1‐Induced Ubiquitination of YTHDF2 to Drive Sorafenib Resistance in Hepatocellular Carcinoma

YTH domain family 2 (YTHDF2) is the first identified N6‐methyladenosine (m(6)A) reader that regulates the status of mRNA. It has been reported that overexpressed YTHDF2 promotes carcinogenesis; yet, its role in hepatocellular carcinoma (HCC) is elusive. Herein, it is demonstrated that YTHDF2 is upre...

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Detalles Bibliográficos
Autores principales: Liao, Yuning, Liu, Yuan, Yu, Cuifu, Lei, Qiucheng, Cheng, Ji, Kong, Weiyao, Yu, Yuanhui, Zhuang, Xuefen, Sun, Wenshuang, Yin, Shusha, Cai, Gengxi, Huang, Hongbiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520652/
https://www.ncbi.nlm.nih.gov/pubmed/37515378
http://dx.doi.org/10.1002/advs.202302025

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