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SPAG17 mediates nuclear translocation of protamines during spermiogenesis

Protamines (PRM1 and PRM2) are small, arginine-rich, nuclear proteins that replace histones in the final stages of spermiogenesis, ensuring chromatin compaction and nuclear remodeling. Defects in protamination lead to increased DNA fragmentation and reduced male fertility. Since efficient sperm prod...

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Detalles Bibliográficos
Autores principales:	Agudo-Rios, Clara, Rogers, Amber, King, Isaiah, Bhagat, Virali, Nguyen, Le My Tu, Córdova-Fletes, Carlos, Krapf, Diego, Strauss, Jerome F., Arévalo, Lena, Merges, Gina Esther, Schorle, Hubert, Roldan, Eduardo R. S., Teves, Maria Eugenia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520709/ https://www.ncbi.nlm.nih.gov/pubmed/37766963 http://dx.doi.org/10.3389/fcell.2023.1125096

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