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Linking drug and food addiction: an overview of the shared neural circuits and behavioral phenotype

Despite a lack of agreement on its definition and inclusion as a specific diagnosable disturbance, the food addiction construct is supported by several neurobiological and behavioral clinical and preclinical findings. Recognizing food addiction is critical to understanding how and why it manifests....

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Autores principales: Passeri, Alice, Municchi, Diana, Cavalieri, Giulia, Babicola, Lucy, Ventura, Rossella, Di Segni, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520727/
https://www.ncbi.nlm.nih.gov/pubmed/37767338
http://dx.doi.org/10.3389/fnbeh.2023.1240748
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author Passeri, Alice
Municchi, Diana
Cavalieri, Giulia
Babicola, Lucy
Ventura, Rossella
Di Segni, Matteo
author_facet Passeri, Alice
Municchi, Diana
Cavalieri, Giulia
Babicola, Lucy
Ventura, Rossella
Di Segni, Matteo
author_sort Passeri, Alice
collection PubMed
description Despite a lack of agreement on its definition and inclusion as a specific diagnosable disturbance, the food addiction construct is supported by several neurobiological and behavioral clinical and preclinical findings. Recognizing food addiction is critical to understanding how and why it manifests. In this overview, we focused on those as follows: 1. the hyperpalatable food effects in food addiction development; 2. specific brain regions involved in both food and drug addiction; and 3. animal models highlighting commonalities between substance use disorders and food addiction. Although results collected through animal studies emerged from protocols differing in several ways, they clearly highlight commonalities in behavioral manifestations and neurobiological alterations between substance use disorders and food addiction characteristics. To develop improved food addiction models, this heterogeneity should be acknowledged and embraced so that research can systematically investigate the role of specific variables in the development of the different behavioral features of addiction-like behavior in preclinical models.
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spelling pubmed-105207272023-09-27 Linking drug and food addiction: an overview of the shared neural circuits and behavioral phenotype Passeri, Alice Municchi, Diana Cavalieri, Giulia Babicola, Lucy Ventura, Rossella Di Segni, Matteo Front Behav Neurosci Behavioral Neuroscience Despite a lack of agreement on its definition and inclusion as a specific diagnosable disturbance, the food addiction construct is supported by several neurobiological and behavioral clinical and preclinical findings. Recognizing food addiction is critical to understanding how and why it manifests. In this overview, we focused on those as follows: 1. the hyperpalatable food effects in food addiction development; 2. specific brain regions involved in both food and drug addiction; and 3. animal models highlighting commonalities between substance use disorders and food addiction. Although results collected through animal studies emerged from protocols differing in several ways, they clearly highlight commonalities in behavioral manifestations and neurobiological alterations between substance use disorders and food addiction characteristics. To develop improved food addiction models, this heterogeneity should be acknowledged and embraced so that research can systematically investigate the role of specific variables in the development of the different behavioral features of addiction-like behavior in preclinical models. Frontiers Media S.A. 2023-09-12 /pmc/articles/PMC10520727/ /pubmed/37767338 http://dx.doi.org/10.3389/fnbeh.2023.1240748 Text en Copyright © 2023 Passeri, Municchi, Cavalieri, Babicola, Ventura and Di Segni. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Behavioral Neuroscience
Passeri, Alice
Municchi, Diana
Cavalieri, Giulia
Babicola, Lucy
Ventura, Rossella
Di Segni, Matteo
Linking drug and food addiction: an overview of the shared neural circuits and behavioral phenotype
title Linking drug and food addiction: an overview of the shared neural circuits and behavioral phenotype
title_full Linking drug and food addiction: an overview of the shared neural circuits and behavioral phenotype
title_fullStr Linking drug and food addiction: an overview of the shared neural circuits and behavioral phenotype
title_full_unstemmed Linking drug and food addiction: an overview of the shared neural circuits and behavioral phenotype
title_short Linking drug and food addiction: an overview of the shared neural circuits and behavioral phenotype
title_sort linking drug and food addiction: an overview of the shared neural circuits and behavioral phenotype
topic Behavioral Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520727/
https://www.ncbi.nlm.nih.gov/pubmed/37767338
http://dx.doi.org/10.3389/fnbeh.2023.1240748
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