Refined semi-lethal aerosol H5N1 influenza model in cynomolgus macaques for evaluation of medical countermeasures

Highly pathogenic avian influenza A H5N1 viruses cause high mortality in humans and have pandemic potential. Effective vaccines and treatments against this threat are urgently needed. Here, we have refined our previously established model of lethal H5N1 infection in cynomolgus macaques. An inhaled a...

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Detalles Bibliográficos
Autores principales: Kanekiyo, Masaru, Gillespie, Rebecca A., Midgett, Morgan, O’Malley, Katherine J., Williams, Connor, Moin, Syed M., Wallace, Megan, Treaster, Luke, Cooper, Kristine, Syeda, Hubza, Kettenburg, Gwenddolen, Rannulu, Hasala, Schmer, Tabitha, Ortiz, Lucia, Da Silva Castanha, Priscila, Corry, Jacqueline, Xia, Mengying, Olsen, Emily, Perez, Daniel, Yun, Gabin, Graham, Barney S., Barratt-Boyes, Simon M., Reed, Douglas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520834/
https://www.ncbi.nlm.nih.gov/pubmed/37766976
http://dx.doi.org/10.1016/j.isci.2023.107830

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