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AKIR-1 regulates proteasome subcellular function in Caenorhabditis elegans

Polyubiquitinated proteins are primarily degraded by the ubiquitin-proteasome system (UPS). Proteasomes are present both in the cytoplasm and nucleus. Here, we investigated mechanisms coordinating proteasome subcellular localization and activity in a multicellular organism. We identified the nuclear...

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Detalles Bibliográficos
Autores principales:	Pispa, Johanna, Mikkonen, Elisa, Arpalahti, Leena, Jin, Congyu, Martínez-Fernández, Carmen, Cerón, Julián, Holmberg, Carina I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520889/ https://www.ncbi.nlm.nih.gov/pubmed/37767001 http://dx.doi.org/10.1016/j.isci.2023.107886

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