Cargando…
Suramin action in African trypanosomes involves a RuvB-like DNA helicase
Suramin is one of the oldest drugs in use today. It is still the treatment of choice for the hemolymphatic stage of African sleeping sickness caused by Trypanosoma brucei rhodesiense, and it is also used for surra in camels caused by Trypanosoma evansi. Yet despite one hundred years of use, suramin&...
Autores principales: | Albisetti, Anna, Hälg, Silvan, Zoltner, Martin, Mäser, Pascal, Wiedemar, Natalie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520940/ https://www.ncbi.nlm.nih.gov/pubmed/37757728 http://dx.doi.org/10.1016/j.ijpddr.2023.09.003 |
Ejemplares similares
-
Structure of Trypanosome Coat Protein VSGsur and Function in Suramin Resistance
por: Zeelen, Johan, et al.
Publicado: (2021) -
Characterization of Plasmodium falciparum ATP-dependent DNA helicase RuvB3
por: Limudomporn, Paviga, et al.
Publicado: (2016) -
ruvA and ruvB mutants specifically impaired for replication fork reversal
por: Le Masson, Marie, et al.
Publicado: (2008) -
Synergistic effect of ATP for RuvA–RuvB–Holliday junction DNA complex formation
por: Iwasa, Takuma, et al.
Publicado: (2015) -
Expression of a specific variant surface glycoprotein has a major impact on suramin sensitivity and endocytosis in Trypanosoma brucei
por: Wiedemar, Natalie, et al.
Publicado: (2019)