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CRISPRe: An innate transcriptional enhancer for endogenous genes in CRISPR-Cas immunity

CRISPR-Cas system has been repurposed to the promising strategy of CRISPR-based transcriptional interference/activation (CRISPRi/CRISPRa) without eliciting DNA breaks that enables Cas complex a block for transcription initiation or elongation, which greatly expands its application fields and values....

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Detalles Bibliográficos
Autores principales:	Li, Dan, Chen, Yihong, Huang, Fei, Wang, Jianmei, Li, Xufeng, Yang, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520945/ https://www.ncbi.nlm.nih.gov/pubmed/37766991 http://dx.doi.org/10.1016/j.isci.2023.107814

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