Generation of Mouse Model of Hemophilia A by Introducing Novel Mutations, Using CRISPR/Nickase Gene Targeting System

Developing mouse models of hemophilia A has been shown to facilitate in vivo studies to explore the probable mechanism(s) underlying the disease and to examine the efficiency of the relevant potential therapeutics. This study aimed to knockout (KO) the coagulation factor viii (fviii) gene in NMRI mi...

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Detalles Bibliográficos
Autores principales: Shamsara, Mehdi, Jamshidizad, Abbas, Rahim-Tayfeh, Aidin, Davari, Maliheh, Rajabi Zangi, Ali, Masoumi, Fatemeh, Zomorodipour, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2023
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520988/
https://www.ncbi.nlm.nih.gov/pubmed/37718768
http://dx.doi.org/10.22074/CELLJ.2023.1999800.1278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520988/
https://www.ncbi.nlm.nih.gov/pubmed/37718768
http://dx.doi.org/10.22074/CELLJ.2023.1999800.1278

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