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Iron-Catalyzed Synthesis of α-Azido α-Amino Esters via the Alkylazidation of Alkenes

[Image: see text] An iron-catalyzed alkylazidation of dehydroamino acids using peroxides as alkyl radical precursors is described. Non-natural azidated amino esters bearing an α-alkyl chain could be obtained in 18–94% yields using TMSN(3) as an azide source. The obtained α-alkyl-α-azide α-amino este...

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Detalles Bibliográficos
Autores principales: Palamini, Pierre, Allouche, Emmanuelle M. D., Waser, Jerome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521020/
https://www.ncbi.nlm.nih.gov/pubmed/37684011
http://dx.doi.org/10.1021/acs.orglett.3c02153

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