Aryl (β,β′,β″-Trifluoro)-tert-butyl: A Candidate Motif for the Discovery of Bioactives

[Image: see text] The (β,β′,β″-trifluoro)-tert-butyl (TFTB) group has received very little attention in the literature. This work presents a direct synthesis of this group and explores its properties. The TFTB group arises when the methyl groups of a tert-butyl moiety are exchanged for fluoromethyl...

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Detalles Bibliográficos
Autores principales: Dobson, Luca S., Zhang, Qingzhi, McKay, Benjamin A., Oke, Oluwayinka, Isanbor, Chukwuemeka, Khan, Mohd Faheem, Piscelli, Bruno A., Cordes, David B., Cormanich, Rodrigo A., Murphy, Cormac D., O’Hagan, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521027/
https://www.ncbi.nlm.nih.gov/pubmed/37682007
http://dx.doi.org/10.1021/acs.orglett.3c02236

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