Cargando…

Ocular Manifestations of Wernicke’s Encephalopathy in a Patient with Hyperemesis Gravidarum Complicating Pregnancy

Wernicke’s encephalopathy (WE) is a condition resulting from thiamine deficiency and has been linked to conditions such as hyperemesis gravidarum, anorexia nervosa, hemodialysis, and chronic alcoholism. The aim of the report is to outline the ocular manifestations of WE. We present the case of a 33-...

Descripción completa

Detalles Bibliográficos
Autores principales: Ye, Ksheeraja, Pius, Chris Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kare Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521135/
https://www.ncbi.nlm.nih.gov/pubmed/37766769
http://dx.doi.org/10.14744/bej.2023.03274
_version_ 1785110069943205888
author Ye, Ksheeraja
Pius, Chris Diana
author_facet Ye, Ksheeraja
Pius, Chris Diana
author_sort Ye, Ksheeraja
collection PubMed
description Wernicke’s encephalopathy (WE) is a condition resulting from thiamine deficiency and has been linked to conditions such as hyperemesis gravidarum, anorexia nervosa, hemodialysis, and chronic alcoholism. The aim of the report is to outline the ocular manifestations of WE. We present the case of a 33-year-old woman, who presented in her second trimester of pregnancy with persistent vomiting, nystagmus, ataxia, global confusion as well as hypotonia, and tremors. She was subsequently diagnosed with WE complicating pregnancy. Ophthalmoscopy showed asymmetric superficial retinal hemorrhages at the peripapillary area in both eyes with associated retinal exudates. On treatment with thiamine supplementation, her systemic condition as well as ocular symptoms resolved. This is a rare case outlining the ocular manifestations of WE. This condition may cause serious, lasting neurologic impairments or death if not properly treated. Only 50% of these pregnancies end in the delivery of healthy offspring. Early diagnosis and treatment of these cases can prevent avertable consequences.
format Online
Article
Text
id pubmed-10521135
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Kare Publishing
record_format MEDLINE/PubMed
spelling pubmed-105211352023-09-27 Ocular Manifestations of Wernicke’s Encephalopathy in a Patient with Hyperemesis Gravidarum Complicating Pregnancy Ye, Ksheeraja Pius, Chris Diana Beyoglu Eye J Case Report Wernicke’s encephalopathy (WE) is a condition resulting from thiamine deficiency and has been linked to conditions such as hyperemesis gravidarum, anorexia nervosa, hemodialysis, and chronic alcoholism. The aim of the report is to outline the ocular manifestations of WE. We present the case of a 33-year-old woman, who presented in her second trimester of pregnancy with persistent vomiting, nystagmus, ataxia, global confusion as well as hypotonia, and tremors. She was subsequently diagnosed with WE complicating pregnancy. Ophthalmoscopy showed asymmetric superficial retinal hemorrhages at the peripapillary area in both eyes with associated retinal exudates. On treatment with thiamine supplementation, her systemic condition as well as ocular symptoms resolved. This is a rare case outlining the ocular manifestations of WE. This condition may cause serious, lasting neurologic impairments or death if not properly treated. Only 50% of these pregnancies end in the delivery of healthy offspring. Early diagnosis and treatment of these cases can prevent avertable consequences. Kare Publishing 2023-09-13 /pmc/articles/PMC10521135/ /pubmed/37766769 http://dx.doi.org/10.14744/bej.2023.03274 Text en Copyright: © 2023 by Beyoglu Eye Training and Research Hospital https://creativecommons.org/licenses/by-nc-sa/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
spellingShingle Case Report
Ye, Ksheeraja
Pius, Chris Diana
Ocular Manifestations of Wernicke’s Encephalopathy in a Patient with Hyperemesis Gravidarum Complicating Pregnancy
title Ocular Manifestations of Wernicke’s Encephalopathy in a Patient with Hyperemesis Gravidarum Complicating Pregnancy
title_full Ocular Manifestations of Wernicke’s Encephalopathy in a Patient with Hyperemesis Gravidarum Complicating Pregnancy
title_fullStr Ocular Manifestations of Wernicke’s Encephalopathy in a Patient with Hyperemesis Gravidarum Complicating Pregnancy
title_full_unstemmed Ocular Manifestations of Wernicke’s Encephalopathy in a Patient with Hyperemesis Gravidarum Complicating Pregnancy
title_short Ocular Manifestations of Wernicke’s Encephalopathy in a Patient with Hyperemesis Gravidarum Complicating Pregnancy
title_sort ocular manifestations of wernicke’s encephalopathy in a patient with hyperemesis gravidarum complicating pregnancy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521135/
https://www.ncbi.nlm.nih.gov/pubmed/37766769
http://dx.doi.org/10.14744/bej.2023.03274
work_keys_str_mv AT yeksheeraja ocularmanifestationsofwernickesencephalopathyinapatientwithhyperemesisgravidarumcomplicatingpregnancy
AT piuschrisdiana ocularmanifestationsofwernickesencephalopathyinapatientwithhyperemesisgravidarumcomplicatingpregnancy