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The molecular details of a novel phosphorylation‐dependent interaction between MRN and the SOSS complex
The repair of double‐strand DNA breaks (DSBs) by homologous recombination is crucial in the maintenance of genome integrity. While the key role of the Mre11‐Rad50‐Nbs1 (MRN) complex in repair is well known, hSSB1 (SOSSB and OBFC2B), one of the main components of the sensor of single‐stranded DNA (SO...
Autores principales: | El‐Kamand, Serene, Adams, Mark N., Matthews, Jacqueline M., Du Plessis, Mar‐Dean, Crossett, Ben, Connolly, Angela, Breen, Natasha, Dudley, Alexander, Richard, Derek J., Gamsjaeger, Roland, Cubeddu, Liza |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521234/ https://www.ncbi.nlm.nih.gov/pubmed/37705456 http://dx.doi.org/10.1002/pro.4782 |
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