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The molecular details of a novel phosphorylation‐dependent interaction between MRN and the SOSS complex

The repair of double‐strand DNA breaks (DSBs) by homologous recombination is crucial in the maintenance of genome integrity. While the key role of the Mre11‐Rad50‐Nbs1 (MRN) complex in repair is well known, hSSB1 (SOSSB and OBFC2B), one of the main components of the sensor of single‐stranded DNA (SO...

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Detalles Bibliográficos
Autores principales: El‐Kamand, Serene, Adams, Mark N., Matthews, Jacqueline M., Du Plessis, Mar‐Dean, Crossett, Ben, Connolly, Angela, Breen, Natasha, Dudley, Alexander, Richard, Derek J., Gamsjaeger, Roland, Cubeddu, Liza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521234/
https://www.ncbi.nlm.nih.gov/pubmed/37705456
http://dx.doi.org/10.1002/pro.4782

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