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Circulating Iron in Patients with Sickle Cell Disease Mediates the Release of Neutrophil Extracellular Traps

INTRODUCTION: Neutrophils promote chronic inflammation and release neutrophil extracellular traps (NETs) that can drive inflammatory responses. Inflammation influences progression of sickle cell disease (SCD), and a role for NETs has been suggested in the onset of vaso-occlusive crisis (VOC). We aim...

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Detalles Bibliográficos
Autores principales: Van Avondt, Kristof, Schimmel, Marein, Bulder, Ingrid, van Mierlo, Gerard, Nur, Erfan, van Bruggen, Robin, Biemond, Bart J., Luken, Brenda M., Zeerleder, Sacha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521246/
https://www.ncbi.nlm.nih.gov/pubmed/37767280
http://dx.doi.org/10.1159/000526760