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Circulating Iron in Patients with Sickle Cell Disease Mediates the Release of Neutrophil Extracellular Traps
INTRODUCTION: Neutrophils promote chronic inflammation and release neutrophil extracellular traps (NETs) that can drive inflammatory responses. Inflammation influences progression of sickle cell disease (SCD), and a role for NETs has been suggested in the onset of vaso-occlusive crisis (VOC). We aim...
Autores principales: | Van Avondt, Kristof, Schimmel, Marein, Bulder, Ingrid, van Mierlo, Gerard, Nur, Erfan, van Bruggen, Robin, Biemond, Bart J., Luken, Brenda M., Zeerleder, Sacha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521246/ https://www.ncbi.nlm.nih.gov/pubmed/37767280 http://dx.doi.org/10.1159/000526760 |
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