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Predictive ability of the Desire to Avoid Pregnancy scale

BACKGROUND: A longstanding gap in the reproductive health field has been the availability of a screening instrument that can reliably predict a person’s likelihood of becoming pregnant. The Desire to Avoid Pregnancy Scale is a new measure; understanding its sensitivity and specificity as a screening...

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Autores principales: Hall, Jennifer A., Barrett, Geraldine, Stephenson, Judith, Rocca, Corinne H., Edelman, Natalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521409/
https://www.ncbi.nlm.nih.gov/pubmed/37749640
http://dx.doi.org/10.1186/s12978-023-01687-9
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author Hall, Jennifer A.
Barrett, Geraldine
Stephenson, Judith
Rocca, Corinne H.
Edelman, Natalie
author_facet Hall, Jennifer A.
Barrett, Geraldine
Stephenson, Judith
Rocca, Corinne H.
Edelman, Natalie
author_sort Hall, Jennifer A.
collection PubMed
description BACKGROUND: A longstanding gap in the reproductive health field has been the availability of a screening instrument that can reliably predict a person’s likelihood of becoming pregnant. The Desire to Avoid Pregnancy Scale is a new measure; understanding its sensitivity and specificity as a screening tool for pregnancy as well as its predictive ability and how this varies by socio-demographic factors is important to inform its implementation. METHODS: This analysis was conducted on a cohort of 994 non-pregnant participants recruited in October 2018 and followed up for one year. The cohort was recruited using social media as well as advertisements in a university, school, abortion clinic and outreach sexual health service. Almost 90% of eligible participants completed follow-up at 12 months; those lost to follow-up were not significantly different on key socio-demographic factors. We used baseline DAP score and a binary variable of whether participants experienced pregnancy during the study to assess the sensitivity, specificity, area under the ROC curve (AUROC) and positive and negative predictive values (PPV and NPV) of the DAP at a range of cut-points. We also examined how the predictive ability of the DAP varied according to socio-demographic factors and by the time frame considered (e.g., pregnancy within 3, 6, 9 and 12 months). RESULTS: At a cut-point of 2 on the 0–4 range of the DAP scale, the DAP had a sensitivity of 0.78, a specificity of 0.81 and an excellent AUROC of 0.87. In this sample the cumulative incidence of pregnancy was 16% (95%CI 13%, 18%) making the PPV 43% and the NPV 95% at this cut-point. The DAP score was the factor most strongly associated with pregnancy, even after age and number of children were taken into account. The association between baseline DAP score and pregnancy did not differ across time frames. CONCLUSIONS: This is the first study to assess the DAP scale as a screening tool and shows that its predictive ability is superior to the limited pre-existing pregnancy prediction tools. Based on our findings, the DAP could be used with a cut-point selected according to the purpose. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12978-023-01687-9.
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spelling pubmed-105214092023-09-27 Predictive ability of the Desire to Avoid Pregnancy scale Hall, Jennifer A. Barrett, Geraldine Stephenson, Judith Rocca, Corinne H. Edelman, Natalie Reprod Health Research BACKGROUND: A longstanding gap in the reproductive health field has been the availability of a screening instrument that can reliably predict a person’s likelihood of becoming pregnant. The Desire to Avoid Pregnancy Scale is a new measure; understanding its sensitivity and specificity as a screening tool for pregnancy as well as its predictive ability and how this varies by socio-demographic factors is important to inform its implementation. METHODS: This analysis was conducted on a cohort of 994 non-pregnant participants recruited in October 2018 and followed up for one year. The cohort was recruited using social media as well as advertisements in a university, school, abortion clinic and outreach sexual health service. Almost 90% of eligible participants completed follow-up at 12 months; those lost to follow-up were not significantly different on key socio-demographic factors. We used baseline DAP score and a binary variable of whether participants experienced pregnancy during the study to assess the sensitivity, specificity, area under the ROC curve (AUROC) and positive and negative predictive values (PPV and NPV) of the DAP at a range of cut-points. We also examined how the predictive ability of the DAP varied according to socio-demographic factors and by the time frame considered (e.g., pregnancy within 3, 6, 9 and 12 months). RESULTS: At a cut-point of 2 on the 0–4 range of the DAP scale, the DAP had a sensitivity of 0.78, a specificity of 0.81 and an excellent AUROC of 0.87. In this sample the cumulative incidence of pregnancy was 16% (95%CI 13%, 18%) making the PPV 43% and the NPV 95% at this cut-point. The DAP score was the factor most strongly associated with pregnancy, even after age and number of children were taken into account. The association between baseline DAP score and pregnancy did not differ across time frames. CONCLUSIONS: This is the first study to assess the DAP scale as a screening tool and shows that its predictive ability is superior to the limited pre-existing pregnancy prediction tools. Based on our findings, the DAP could be used with a cut-point selected according to the purpose. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12978-023-01687-9. BioMed Central 2023-09-25 /pmc/articles/PMC10521409/ /pubmed/37749640 http://dx.doi.org/10.1186/s12978-023-01687-9 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Hall, Jennifer A.
Barrett, Geraldine
Stephenson, Judith
Rocca, Corinne H.
Edelman, Natalie
Predictive ability of the Desire to Avoid Pregnancy scale
title Predictive ability of the Desire to Avoid Pregnancy scale
title_full Predictive ability of the Desire to Avoid Pregnancy scale
title_fullStr Predictive ability of the Desire to Avoid Pregnancy scale
title_full_unstemmed Predictive ability of the Desire to Avoid Pregnancy scale
title_short Predictive ability of the Desire to Avoid Pregnancy scale
title_sort predictive ability of the desire to avoid pregnancy scale
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521409/
https://www.ncbi.nlm.nih.gov/pubmed/37749640
http://dx.doi.org/10.1186/s12978-023-01687-9
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