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Dietary treatment postpartum in women with obesity reduces weight and prevents weight gain: a randomised controlled trial

BACKGROUND: Women with pre-pregnancy obesity have an increased risk of retaining or gaining weight postpartum and may benefit from weight loss treatment. However, evidence is lacking for weight loss strategies in women with BMIs in the higher obesity classes. A dietary treatment for postpartum weigh...

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Autores principales: Øhman, Elisabeth A., Fossli, Maria, Ottestad, Inger, Holven, Kirsten B., Ulven, Stine M., Løland, Beate F., Brekke, Hilde K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521473/
https://www.ncbi.nlm.nih.gov/pubmed/37752466
http://dx.doi.org/10.1186/s12884-023-05976-w
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author Øhman, Elisabeth A.
Fossli, Maria
Ottestad, Inger
Holven, Kirsten B.
Ulven, Stine M.
Løland, Beate F.
Brekke, Hilde K.
author_facet Øhman, Elisabeth A.
Fossli, Maria
Ottestad, Inger
Holven, Kirsten B.
Ulven, Stine M.
Løland, Beate F.
Brekke, Hilde K.
author_sort Øhman, Elisabeth A.
collection PubMed
description BACKGROUND: Women with pre-pregnancy obesity have an increased risk of retaining or gaining weight postpartum and may benefit from weight loss treatment. However, evidence is lacking for weight loss strategies in women with BMIs in the higher obesity classes. A dietary treatment for postpartum weight loss resulted in a 10% weight reduction in lactating women with a mean BMI of 30 kg/m(2). We aimed to examine the effects of this dietary treatment on changes in weight, markers of lipid and glucose metabolism, waist and hip circumference and postpartum weight retention (PPWR) in postpartum women with higher BMIs than tested previously. METHODS: At baseline, approximately 8 weeks postpartum, 29 women with a mean (SD) BMI = 40.0 (5.2) kg/m(2) were randomised to a 12-week dietary treatment (n 14) or to a control treatment (n 15). Measurements were made at baseline and after 3 and 12 months. Data was analysed using mixed model. RESULTS: The mean weight change in the diet group was -2.3 (3.1) kg compared to 1.7 (3.1) kg in the control group after 3 months (P = 0.003) and -4.2 (5.6) kg compared to 4.8 (11.8) kg in the control group after 12 months (P = 0.02). The dietary treatment led to reduced waist circumference (P < 0.04) and PPWR (P < 0.01) compared to the control treatment at both time points. The treatment lowered fasting blood glucose at 12 months (P = 0.007) as the only effect on markers of lipid and glucose metabolism. CONCLUSION: The dietary treatment postpartum reduced weight and prevented weight retention or weight gain in women with obesity. TRIAL REGISTRATION: The trial was retrospectively registered at ClinicalTrials.gov (NCT03579667) 06/07/2018. GRAPHICAL ABSTRACT: In a randomised, controlled trial, 29 postpartum women with obesity were allocated to a dietary treatment or a control treatment. The dietary treatment reduced weight and prevented postpartum weight retention or weight gain after 12 months. Reference: Adapted from “Randomized, Placebo-Controlled, Parallel Study Design (2 Arms, Graphical)”, by BioRender.com (2022). Retrieved from https://app.biorender.com/biorender-templates. [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12884-023-05976-w.
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spelling pubmed-105214732023-09-27 Dietary treatment postpartum in women with obesity reduces weight and prevents weight gain: a randomised controlled trial Øhman, Elisabeth A. Fossli, Maria Ottestad, Inger Holven, Kirsten B. Ulven, Stine M. Løland, Beate F. Brekke, Hilde K. BMC Pregnancy Childbirth Research BACKGROUND: Women with pre-pregnancy obesity have an increased risk of retaining or gaining weight postpartum and may benefit from weight loss treatment. However, evidence is lacking for weight loss strategies in women with BMIs in the higher obesity classes. A dietary treatment for postpartum weight loss resulted in a 10% weight reduction in lactating women with a mean BMI of 30 kg/m(2). We aimed to examine the effects of this dietary treatment on changes in weight, markers of lipid and glucose metabolism, waist and hip circumference and postpartum weight retention (PPWR) in postpartum women with higher BMIs than tested previously. METHODS: At baseline, approximately 8 weeks postpartum, 29 women with a mean (SD) BMI = 40.0 (5.2) kg/m(2) were randomised to a 12-week dietary treatment (n 14) or to a control treatment (n 15). Measurements were made at baseline and after 3 and 12 months. Data was analysed using mixed model. RESULTS: The mean weight change in the diet group was -2.3 (3.1) kg compared to 1.7 (3.1) kg in the control group after 3 months (P = 0.003) and -4.2 (5.6) kg compared to 4.8 (11.8) kg in the control group after 12 months (P = 0.02). The dietary treatment led to reduced waist circumference (P < 0.04) and PPWR (P < 0.01) compared to the control treatment at both time points. The treatment lowered fasting blood glucose at 12 months (P = 0.007) as the only effect on markers of lipid and glucose metabolism. CONCLUSION: The dietary treatment postpartum reduced weight and prevented weight retention or weight gain in women with obesity. TRIAL REGISTRATION: The trial was retrospectively registered at ClinicalTrials.gov (NCT03579667) 06/07/2018. GRAPHICAL ABSTRACT: In a randomised, controlled trial, 29 postpartum women with obesity were allocated to a dietary treatment or a control treatment. The dietary treatment reduced weight and prevented postpartum weight retention or weight gain after 12 months. Reference: Adapted from “Randomized, Placebo-Controlled, Parallel Study Design (2 Arms, Graphical)”, by BioRender.com (2022). Retrieved from https://app.biorender.com/biorender-templates. [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12884-023-05976-w. BioMed Central 2023-09-26 /pmc/articles/PMC10521473/ /pubmed/37752466 http://dx.doi.org/10.1186/s12884-023-05976-w Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Øhman, Elisabeth A.
Fossli, Maria
Ottestad, Inger
Holven, Kirsten B.
Ulven, Stine M.
Løland, Beate F.
Brekke, Hilde K.
Dietary treatment postpartum in women with obesity reduces weight and prevents weight gain: a randomised controlled trial
title Dietary treatment postpartum in women with obesity reduces weight and prevents weight gain: a randomised controlled trial
title_full Dietary treatment postpartum in women with obesity reduces weight and prevents weight gain: a randomised controlled trial
title_fullStr Dietary treatment postpartum in women with obesity reduces weight and prevents weight gain: a randomised controlled trial
title_full_unstemmed Dietary treatment postpartum in women with obesity reduces weight and prevents weight gain: a randomised controlled trial
title_short Dietary treatment postpartum in women with obesity reduces weight and prevents weight gain: a randomised controlled trial
title_sort dietary treatment postpartum in women with obesity reduces weight and prevents weight gain: a randomised controlled trial
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521473/
https://www.ncbi.nlm.nih.gov/pubmed/37752466
http://dx.doi.org/10.1186/s12884-023-05976-w
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