Hypoxia-induced TMTC3 expression in esophageal squamous cell carcinoma potentiates tumor angiogenesis through Rho GTPase/STAT3/VEGFA pathway

BACKGROUND: Hypoxia is one of most typical features in the tumor microenvironment of solid tumor and an inducer of endoplasmic reticulum (ER) stress, and HIF-1α functions as a key transcription factor regulator to promote tumor angiogenesis in the adaptive response to hypoxia. Increasing evidence ha...

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Detalles Bibliográficos
Autores principales: Yuan, Hongyu, Zhao, Zitong, Xu, Jing, Zhang, Ruiping, Ma, Liying, Han, Jing, Zhao, Weihong, Guo, Mingzhou, Song, Yongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521530/
https://www.ncbi.nlm.nih.gov/pubmed/37752569
http://dx.doi.org/10.1186/s13046-023-02821-y

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