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Capsular warning syndrome—a case of atrial fibrillation and corona radiata infarct

BACKGROUND: Capsular warning syndrome (CWS) is a rare clinical syndrome characterised by recurrent and transient episodes of focal neurological deficits with high risk of infarction. The exact physiological mechanism of CWS remains unclear but is most commonly believed to be a result of haemodynamic...

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Autores principales: Tan, Sarah En Mei, Heng, Kenneth Wei Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521567/
https://www.ncbi.nlm.nih.gov/pubmed/37752459
http://dx.doi.org/10.1186/s12245-023-00541-w
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author Tan, Sarah En Mei
Heng, Kenneth Wei Jian
author_facet Tan, Sarah En Mei
Heng, Kenneth Wei Jian
author_sort Tan, Sarah En Mei
collection PubMed
description BACKGROUND: Capsular warning syndrome (CWS) is a rare clinical syndrome characterised by recurrent and transient episodes of focal neurological deficits with high risk of infarction. The exact physiological mechanism of CWS remains unclear but is most commonly believed to be a result of haemodynamic insufficiency in diseased, small penetrating vessels. There are no defined treatment guidelines or established effective therapy. CASE PRESENTATION: We describe the case of a 65-year-old man who presented to the emergency department with recurrent episodes of dysarthria coupled with right facial droop and right-sided weakness. Symptoms recurred a total of ten times within a span of 3 h. He had new onset atrial fibrillation. An initial cerebral angiogram showed mild intracranial atherosclerotic disease with no proximal large vessel occlusion or acute infarct. Magnetic resonance imaging 1 h later demonstrated an infarct in the left corona radiata. CONCLUSIONS: This case illustrates an uncommon etiology of CWS. We will also discuss the lack of consensus in treatment options for CWS to mitigate a complete stroke.
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spelling pubmed-105215672023-09-27 Capsular warning syndrome—a case of atrial fibrillation and corona radiata infarct Tan, Sarah En Mei Heng, Kenneth Wei Jian Int J Emerg Med Case Report BACKGROUND: Capsular warning syndrome (CWS) is a rare clinical syndrome characterised by recurrent and transient episodes of focal neurological deficits with high risk of infarction. The exact physiological mechanism of CWS remains unclear but is most commonly believed to be a result of haemodynamic insufficiency in diseased, small penetrating vessels. There are no defined treatment guidelines or established effective therapy. CASE PRESENTATION: We describe the case of a 65-year-old man who presented to the emergency department with recurrent episodes of dysarthria coupled with right facial droop and right-sided weakness. Symptoms recurred a total of ten times within a span of 3 h. He had new onset atrial fibrillation. An initial cerebral angiogram showed mild intracranial atherosclerotic disease with no proximal large vessel occlusion or acute infarct. Magnetic resonance imaging 1 h later demonstrated an infarct in the left corona radiata. CONCLUSIONS: This case illustrates an uncommon etiology of CWS. We will also discuss the lack of consensus in treatment options for CWS to mitigate a complete stroke. Springer Berlin Heidelberg 2023-09-26 /pmc/articles/PMC10521567/ /pubmed/37752459 http://dx.doi.org/10.1186/s12245-023-00541-w Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Tan, Sarah En Mei
Heng, Kenneth Wei Jian
Capsular warning syndrome—a case of atrial fibrillation and corona radiata infarct
title Capsular warning syndrome—a case of atrial fibrillation and corona radiata infarct
title_full Capsular warning syndrome—a case of atrial fibrillation and corona radiata infarct
title_fullStr Capsular warning syndrome—a case of atrial fibrillation and corona radiata infarct
title_full_unstemmed Capsular warning syndrome—a case of atrial fibrillation and corona radiata infarct
title_short Capsular warning syndrome—a case of atrial fibrillation and corona radiata infarct
title_sort capsular warning syndrome—a case of atrial fibrillation and corona radiata infarct
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521567/
https://www.ncbi.nlm.nih.gov/pubmed/37752459
http://dx.doi.org/10.1186/s12245-023-00541-w
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