Influenza A(H5N1) Virus Infections in 2 Free-Ranging Black Bears (Ursus americanus), Quebec, Canada

Wholly Eurasian highly pathogemic avian influenza H5N1 clade 2.3.4.4b virus was isolated from 2 free-ranging black bears with meningoencephalitis in Quebec, Canada. We found that isolates from both animals had the D701N mutation in the polymerase basic 2 gene, previously known to promote adaptation...

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Autores principales: Jakobek, Benjamin T., Berhane, Yohannes, Nadeau, Marie-Soleil, Embury-Hyatt, Carissa, Lung, Oliver, Xu, Wanhong, Lair, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2023
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521626/
https://www.ncbi.nlm.nih.gov/pubmed/37735770
http://dx.doi.org/10.3201/eid2910.230548
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author Jakobek, Benjamin T.
Berhane, Yohannes
Nadeau, Marie-Soleil
Embury-Hyatt, Carissa
Lung, Oliver
Xu, Wanhong
Lair, Stéphane
author_facet Jakobek, Benjamin T.
Berhane, Yohannes
Nadeau, Marie-Soleil
Embury-Hyatt, Carissa
Lung, Oliver
Xu, Wanhong
Lair, Stéphane
author_sort Jakobek, Benjamin T.
collection PubMed
description Wholly Eurasian highly pathogemic avian influenza H5N1 clade 2.3.4.4b virus was isolated from 2 free-ranging black bears with meningoencephalitis in Quebec, Canada. We found that isolates from both animals had the D701N mutation in the polymerase basic 2 gene, previously known to promote adaptation of H5N1 viruses to mammal hosts.
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spelling pubmed-105216262023-10-01 Influenza A(H5N1) Virus Infections in 2 Free-Ranging Black Bears (Ursus americanus), Quebec, Canada Jakobek, Benjamin T. Berhane, Yohannes Nadeau, Marie-Soleil Embury-Hyatt, Carissa Lung, Oliver Xu, Wanhong Lair, Stéphane Emerg Infect Dis Dispatch Wholly Eurasian highly pathogemic avian influenza H5N1 clade 2.3.4.4b virus was isolated from 2 free-ranging black bears with meningoencephalitis in Quebec, Canada. We found that isolates from both animals had the D701N mutation in the polymerase basic 2 gene, previously known to promote adaptation of H5N1 viruses to mammal hosts. Centers for Disease Control and Prevention 2023-10 /pmc/articles/PMC10521626/ /pubmed/37735770 http://dx.doi.org/10.3201/eid2910.230548 Text en https://creativecommons.org/licenses/by/4.0/Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Jakobek, Benjamin T.
Berhane, Yohannes
Nadeau, Marie-Soleil
Embury-Hyatt, Carissa
Lung, Oliver
Xu, Wanhong
Lair, Stéphane
Influenza A(H5N1) Virus Infections in 2 Free-Ranging Black Bears (Ursus americanus), Quebec, Canada
title Influenza A(H5N1) Virus Infections in 2 Free-Ranging Black Bears (Ursus americanus), Quebec, Canada
title_full Influenza A(H5N1) Virus Infections in 2 Free-Ranging Black Bears (Ursus americanus), Quebec, Canada
title_fullStr Influenza A(H5N1) Virus Infections in 2 Free-Ranging Black Bears (Ursus americanus), Quebec, Canada
title_full_unstemmed Influenza A(H5N1) Virus Infections in 2 Free-Ranging Black Bears (Ursus americanus), Quebec, Canada
title_short Influenza A(H5N1) Virus Infections in 2 Free-Ranging Black Bears (Ursus americanus), Quebec, Canada
title_sort influenza a(h5n1) virus infections in 2 free-ranging black bears (ursus americanus), quebec, canada
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521626/
https://www.ncbi.nlm.nih.gov/pubmed/37735770
http://dx.doi.org/10.3201/eid2910.230548
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