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Perspective: The Rapidly Expanding Need for Biosecurity by Design

Advancing biotechnologies are revolutionizing not only health and medicine, but also many different sectors such as agriculture, energy, chemistry, and textiles. As synthetic biology is leveraged as a programmable platform for the creation and biodesign of high-value biological medicines, foods, and...

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Detalles Bibliográficos
Autor principal: DiEuliis, Diane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521668/
https://www.ncbi.nlm.nih.gov/pubmed/37850149
http://dx.doi.org/10.34133/2022/9809058
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author DiEuliis, Diane
author_facet DiEuliis, Diane
author_sort DiEuliis, Diane
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description Advancing biotechnologies are revolutionizing not only health and medicine, but also many different sectors such as agriculture, energy, chemistry, and textiles. As synthetic biology is leveraged as a programmable platform for the creation and biodesign of high-value biological medicines, foods, and commodities, the world is facing new territory in terms of ensuring the safety and security of both novel and engineered biological organisms, as well as the biological and digital platforms in which they are designed. Biosecurity practices and policies have traditionally revolved around preventing the misuse of biological pathogens, primarily through controlling access to pathogens. The advent of biodesign capabilities, such as gene editors, gene synthesis capabilities, and genetic engineering, requires a reevaluation of traditional biosecurity policies to mitigate risks associated with such engineering of biological entities. Here, features of “Biosecurity by Design” approaches are described, including the application of risk/benefit analysis and risk mitigation, post-COVID opportunities, and ethical global norms in the progression of biodesign and growing bioeconomies.
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spelling pubmed-105216682023-10-17 Perspective: The Rapidly Expanding Need for Biosecurity by Design DiEuliis, Diane Biodes Res Perspective Advancing biotechnologies are revolutionizing not only health and medicine, but also many different sectors such as agriculture, energy, chemistry, and textiles. As synthetic biology is leveraged as a programmable platform for the creation and biodesign of high-value biological medicines, foods, and commodities, the world is facing new territory in terms of ensuring the safety and security of both novel and engineered biological organisms, as well as the biological and digital platforms in which they are designed. Biosecurity practices and policies have traditionally revolved around preventing the misuse of biological pathogens, primarily through controlling access to pathogens. The advent of biodesign capabilities, such as gene editors, gene synthesis capabilities, and genetic engineering, requires a reevaluation of traditional biosecurity policies to mitigate risks associated with such engineering of biological entities. Here, features of “Biosecurity by Design” approaches are described, including the application of risk/benefit analysis and risk mitigation, post-COVID opportunities, and ethical global norms in the progression of biodesign and growing bioeconomies. AAAS 2022-05-25 /pmc/articles/PMC10521668/ /pubmed/37850149 http://dx.doi.org/10.34133/2022/9809058 Text en Copyright © 2022 Diane DiEuliis. https://creativecommons.org/licenses/by/4.0/Exclusive Licensee Nanjing Agricultural University. Distributed under a Creative Commons Attribution License (CC BY 4.0). (https://creativecommons.org/licenses/by/4.0/)
spellingShingle Perspective
DiEuliis, Diane
Perspective: The Rapidly Expanding Need for Biosecurity by Design
title Perspective: The Rapidly Expanding Need for Biosecurity by Design
title_full Perspective: The Rapidly Expanding Need for Biosecurity by Design
title_fullStr Perspective: The Rapidly Expanding Need for Biosecurity by Design
title_full_unstemmed Perspective: The Rapidly Expanding Need for Biosecurity by Design
title_short Perspective: The Rapidly Expanding Need for Biosecurity by Design
title_sort perspective: the rapidly expanding need for biosecurity by design
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521668/
https://www.ncbi.nlm.nih.gov/pubmed/37850149
http://dx.doi.org/10.34133/2022/9809058
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