What Have We Learned from Design of Function in Large Proteins?

The overarching goal of computational protein design is to gain complete control over protein structure and function. The majority of sophisticated binders and enzymes, however, are large and exhibit diverse and complex folds that defy atomistic design calculations. Encouragingly, recent strategies...

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Detalles Bibliográficos
Autores principales: Khersonsky, Olga, Fleishman, Sarel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521758/
https://www.ncbi.nlm.nih.gov/pubmed/37850148
http://dx.doi.org/10.34133/2022/9787581

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