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Plasminogen Receptors Promote Lipoprotein(a) Uptake by Enhancing Surface Binding and Facilitating Macropinocytosis

BACKGROUND: High levels of Lp(a) (lipoprotein(a)) are associated with multiple forms of cardiovascular disease. Lp(a) consists of an apoB(100)-containing particle attached to the plasminogen homologue apo(a). The pathways for Lp(a) clearance are not well understood. We previously discovered that the...

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Detalles Bibliográficos
Autores principales: Siddiqui, Halima, Deo, Nikita, Rutledge, Malcolm T., Williams, Michael J.A., Redpath, Gregory M.I., McCormick, Sally P.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521804/
https://www.ncbi.nlm.nih.gov/pubmed/37589135
http://dx.doi.org/10.1161/ATVBAHA.123.319344

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