Functional characterization of a single nucleotide polymorphism associated with Alzheimer’s disease in a hiPSC-based neuron model

Neurodegenerative diseases encompass a group of debilitating conditions resulting from progressive nerve cell death. Of these, Alzheimer’s disease (AD) occurs most frequently, but is currently incurable and has limited treatment success. Late onset AD, the most common form, is highly heritable but i...

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Detalles Bibliográficos
Autores principales: Stolzenburg, Lindsay R., Esmaeeli, Sahar, Kulkarni, Ameya S., Murphy, Erin, Kwon, Taekyung, Preiss, Christina, Bahnassawy, Lamiaa, Stender, Joshua D., Manos, Justine D., Reinhardt, Peter, Rahimov, Fedik, Waring, Jeffrey F., Ramathal, Cyril Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521995/
https://www.ncbi.nlm.nih.gov/pubmed/37751459
http://dx.doi.org/10.1371/journal.pone.0291029

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