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Towards a potent and rapidly reversible Dexmedetomidine-based general anesthetic

Clinically useful anesthetics are associated with delirium and cognitive decline in the elderly. Dexmedetomidine (Dex), an α(2) adrenergic receptor agonist, is an intravenous sedative with analgesic properties. Dex is associated with a lower incidence of delirium in the elderly. In this study, we fi...

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Detalles Bibliográficos
Autores principales: Xie, Zheng, Fong, Robert, Fox, Aaron P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522005/
https://www.ncbi.nlm.nih.gov/pubmed/37751454
http://dx.doi.org/10.1371/journal.pone.0291827