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The contribution of ultrasonographic findings to the prognosis of subacute thyroiditis
OBJECTIVE: Ultrasound assessment plays an important role in the diagnosis, and monitoring of subacute thyroiditis (SAT). However, the relationship between ultrasonographic findings and severity or prognosis of the disease is not known. The aim of the present study was to evaluate the relationship be...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Endocrinologia e Metabologia
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522218/ https://www.ncbi.nlm.nih.gov/pubmed/32555998 http://dx.doi.org/10.20945/2359-3997000000253 |
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author | Sencar, Muhammed Erkam Calapkulu, Murat Sakiz, Davut Akhanli, Pinar Hepsen, Sema Duger, Hakan Unsal, Ilknur Ozturk Kizilgul, Muhammed Cakal, Erman |
author_facet | Sencar, Muhammed Erkam Calapkulu, Murat Sakiz, Davut Akhanli, Pinar Hepsen, Sema Duger, Hakan Unsal, Ilknur Ozturk Kizilgul, Muhammed Cakal, Erman |
author_sort | Sencar, Muhammed Erkam |
collection | PubMed |
description | OBJECTIVE: Ultrasound assessment plays an important role in the diagnosis, and monitoring of subacute thyroiditis (SAT). However, the relationship between ultrasonographic findings and severity or prognosis of the disease is not known. The aim of the present study was to evaluate the relationship between bilateral and unilateral disease involvement and severity and prognosis of the disease. SUBJECTS AND METHODS: The initial laboratory values, ultrasonographic findings and long-term outcomes of 247 SAT patients were evaluated retrospectively. RESULTS: In the ultrasonographic evaluation, bilateral involvement was detected in 154 patients, and unilateral involvement in 93 patients at the time of diagnosis. No significant difference was found between patients with bilateral or unilateral disease at the time of diagnosis in respect of the initial acute phase reactants. FT4 was significantly higher and TSH was significantly lower in the group with bilateral disease. Bilobar or unilobar disease on ultrasound at the time of diagnosis was not found to be a risk factor for permanent hypothyroidism or recurrence. The mean thyroid volume was determined to be 22.5 ± 10 cm(3) at the beginning of treatment, and 11.2 ± 8 cm(3) at the end of treatment. The initial thyroid volume and the thyroid volume at the end of treatment were significantly lower in patients who developed hypothyroidism. CONCLUSION: There was no relationship between initial acute phase reactants and bilateral or unilateral involvement of the disease. FT4 levels were found to be associated with the extension of the disease. The risk of recurrence and permanent hypothyroidism are not associated with the initial ultrasonographic aspect. Arch Endocrinol Metab. 2020;64(3):306-11 |
format | Online Article Text |
id | pubmed-10522218 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Sociedade Brasileira de Endocrinologia e Metabologia |
record_format | MEDLINE/PubMed |
spelling | pubmed-105222182023-09-27 The contribution of ultrasonographic findings to the prognosis of subacute thyroiditis Sencar, Muhammed Erkam Calapkulu, Murat Sakiz, Davut Akhanli, Pinar Hepsen, Sema Duger, Hakan Unsal, Ilknur Ozturk Kizilgul, Muhammed Cakal, Erman Arch Endocrinol Metab Original Article OBJECTIVE: Ultrasound assessment plays an important role in the diagnosis, and monitoring of subacute thyroiditis (SAT). However, the relationship between ultrasonographic findings and severity or prognosis of the disease is not known. The aim of the present study was to evaluate the relationship between bilateral and unilateral disease involvement and severity and prognosis of the disease. SUBJECTS AND METHODS: The initial laboratory values, ultrasonographic findings and long-term outcomes of 247 SAT patients were evaluated retrospectively. RESULTS: In the ultrasonographic evaluation, bilateral involvement was detected in 154 patients, and unilateral involvement in 93 patients at the time of diagnosis. No significant difference was found between patients with bilateral or unilateral disease at the time of diagnosis in respect of the initial acute phase reactants. FT4 was significantly higher and TSH was significantly lower in the group with bilateral disease. Bilobar or unilobar disease on ultrasound at the time of diagnosis was not found to be a risk factor for permanent hypothyroidism or recurrence. The mean thyroid volume was determined to be 22.5 ± 10 cm(3) at the beginning of treatment, and 11.2 ± 8 cm(3) at the end of treatment. The initial thyroid volume and the thyroid volume at the end of treatment were significantly lower in patients who developed hypothyroidism. CONCLUSION: There was no relationship between initial acute phase reactants and bilateral or unilateral involvement of the disease. FT4 levels were found to be associated with the extension of the disease. The risk of recurrence and permanent hypothyroidism are not associated with the initial ultrasonographic aspect. Arch Endocrinol Metab. 2020;64(3):306-11 Sociedade Brasileira de Endocrinologia e Metabologia 2020-06-05 /pmc/articles/PMC10522218/ /pubmed/32555998 http://dx.doi.org/10.20945/2359-3997000000253 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Sencar, Muhammed Erkam Calapkulu, Murat Sakiz, Davut Akhanli, Pinar Hepsen, Sema Duger, Hakan Unsal, Ilknur Ozturk Kizilgul, Muhammed Cakal, Erman The contribution of ultrasonographic findings to the prognosis of subacute thyroiditis |
title | The contribution of ultrasonographic findings to the prognosis of subacute thyroiditis |
title_full | The contribution of ultrasonographic findings to the prognosis of subacute thyroiditis |
title_fullStr | The contribution of ultrasonographic findings to the prognosis of subacute thyroiditis |
title_full_unstemmed | The contribution of ultrasonographic findings to the prognosis of subacute thyroiditis |
title_short | The contribution of ultrasonographic findings to the prognosis of subacute thyroiditis |
title_sort | contribution of ultrasonographic findings to the prognosis of subacute thyroiditis |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522218/ https://www.ncbi.nlm.nih.gov/pubmed/32555998 http://dx.doi.org/10.20945/2359-3997000000253 |
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