Nutritional genomics, inflammation and obesity

The Human Genome Project has significantly broadened our understanding of the molecular aspects regulating the homeostasis and the pathophysiology of different clinical conditions. Consequently, the field of nutrition has been strongly influenced by such improvements in knowledge – especially for de...

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Autores principales: Corrêa, Telma Angelina Faraldo, Quintanilha, Bruna Jardim, Norde, Marina Maintinguer, Pinhel, Marcela Augusta de Souza, Nonino, Carla Barbosa, Rogero, Marcelo Macedo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Endocrinologia e Metabologia 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522224/
https://www.ncbi.nlm.nih.gov/pubmed/32555987
http://dx.doi.org/10.20945/2359-3997000000255
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author Corrêa, Telma Angelina Faraldo
Quintanilha, Bruna Jardim
Norde, Marina Maintinguer
Pinhel, Marcela Augusta de Souza
Nonino, Carla Barbosa
Rogero, Marcelo Macedo
author_facet Corrêa, Telma Angelina Faraldo
Quintanilha, Bruna Jardim
Norde, Marina Maintinguer
Pinhel, Marcela Augusta de Souza
Nonino, Carla Barbosa
Rogero, Marcelo Macedo
author_sort Corrêa, Telma Angelina Faraldo
collection PubMed
description The Human Genome Project has significantly broadened our understanding of the molecular aspects regulating the homeostasis and the pathophysiology of different clinical conditions. Consequently, the field of nutrition has been strongly influenced by such improvements in knowledge – especially for determining how nutrients act at the molecular level in different conditions, such as obesity, type 2 diabetes, cardiovascular disease, and cancer. In this manner, characterizing how the genome influences the diet and vice-versa provides insights about the molecular mechanisms involved in chronic inflammation-related diseases. Therefore, the present review aims to discuss the potential application of Nutritional Genomics to modulate obesity-related inflammatory responses. Arch Endocrinol Metab. 2020;64(3):205-22
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spelling pubmed-105222242023-09-27 Nutritional genomics, inflammation and obesity Corrêa, Telma Angelina Faraldo Quintanilha, Bruna Jardim Norde, Marina Maintinguer Pinhel, Marcela Augusta de Souza Nonino, Carla Barbosa Rogero, Marcelo Macedo Arch Endocrinol Metab Review The Human Genome Project has significantly broadened our understanding of the molecular aspects regulating the homeostasis and the pathophysiology of different clinical conditions. Consequently, the field of nutrition has been strongly influenced by such improvements in knowledge – especially for determining how nutrients act at the molecular level in different conditions, such as obesity, type 2 diabetes, cardiovascular disease, and cancer. In this manner, characterizing how the genome influences the diet and vice-versa provides insights about the molecular mechanisms involved in chronic inflammation-related diseases. Therefore, the present review aims to discuss the potential application of Nutritional Genomics to modulate obesity-related inflammatory responses. Arch Endocrinol Metab. 2020;64(3):205-22 Sociedade Brasileira de Endocrinologia e Metabologia 2020-06-05 /pmc/articles/PMC10522224/ /pubmed/32555987 http://dx.doi.org/10.20945/2359-3997000000255 Text en https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Corrêa, Telma Angelina Faraldo
Quintanilha, Bruna Jardim
Norde, Marina Maintinguer
Pinhel, Marcela Augusta de Souza
Nonino, Carla Barbosa
Rogero, Marcelo Macedo
Nutritional genomics, inflammation and obesity
title Nutritional genomics, inflammation and obesity
title_full Nutritional genomics, inflammation and obesity
title_fullStr Nutritional genomics, inflammation and obesity
title_full_unstemmed Nutritional genomics, inflammation and obesity
title_short Nutritional genomics, inflammation and obesity
title_sort nutritional genomics, inflammation and obesity
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522224/
https://www.ncbi.nlm.nih.gov/pubmed/32555987
http://dx.doi.org/10.20945/2359-3997000000255
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