Cargando…

Gene expression mapping of the neuroectoderm across phyla – conservation and divergence of early brain anlagen between insects and vertebrates

Gene expression has been employed for homologizing body regions across bilateria. The molecular comparison of vertebrate and fly brains has led to a number of disputed homology hypotheses. Data from the fly Drosophila melanogaster have recently been complemented by extensive data from the red flour...

Descripción completa

Detalles Bibliográficos
Autores principales: Posnien, Nico, Hunnekuhl, Vera S, Bucher, Gregor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522337/
https://www.ncbi.nlm.nih.gov/pubmed/37750868
http://dx.doi.org/10.7554/eLife.92242
_version_ 1785110337063747584
author Posnien, Nico
Hunnekuhl, Vera S
Bucher, Gregor
author_facet Posnien, Nico
Hunnekuhl, Vera S
Bucher, Gregor
author_sort Posnien, Nico
collection PubMed
description Gene expression has been employed for homologizing body regions across bilateria. The molecular comparison of vertebrate and fly brains has led to a number of disputed homology hypotheses. Data from the fly Drosophila melanogaster have recently been complemented by extensive data from the red flour beetle Tribolium castaneum with its more insect-typical development. In this review, we revisit the molecular mapping of the neuroectoderm of insects and vertebrates to reconsider homology hypotheses. We claim that the protocerebrum is non-segmental and homologous to the vertebrate fore- and midbrain. The boundary between antennal and ocular regions correspond to the vertebrate mid-hindbrain boundary while the deutocerebrum represents the anterior-most ganglion with serial homology to the trunk. The insect head placode is shares common embryonic origin with the vertebrate adenohypophyseal placode. Intriguingly, vertebrate eyes develop from a different region compared to the insect compound eyes calling organ homology into question. Finally, we suggest a molecular re-definition of the classic concepts of archi- and prosocerebrum.
format Online
Article
Text
id pubmed-10522337
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher eLife Sciences Publications, Ltd
record_format MEDLINE/PubMed
spelling pubmed-105223372023-09-27 Gene expression mapping of the neuroectoderm across phyla – conservation and divergence of early brain anlagen between insects and vertebrates Posnien, Nico Hunnekuhl, Vera S Bucher, Gregor eLife Developmental Biology Gene expression has been employed for homologizing body regions across bilateria. The molecular comparison of vertebrate and fly brains has led to a number of disputed homology hypotheses. Data from the fly Drosophila melanogaster have recently been complemented by extensive data from the red flour beetle Tribolium castaneum with its more insect-typical development. In this review, we revisit the molecular mapping of the neuroectoderm of insects and vertebrates to reconsider homology hypotheses. We claim that the protocerebrum is non-segmental and homologous to the vertebrate fore- and midbrain. The boundary between antennal and ocular regions correspond to the vertebrate mid-hindbrain boundary while the deutocerebrum represents the anterior-most ganglion with serial homology to the trunk. The insect head placode is shares common embryonic origin with the vertebrate adenohypophyseal placode. Intriguingly, vertebrate eyes develop from a different region compared to the insect compound eyes calling organ homology into question. Finally, we suggest a molecular re-definition of the classic concepts of archi- and prosocerebrum. eLife Sciences Publications, Ltd 2023-09-26 /pmc/articles/PMC10522337/ /pubmed/37750868 http://dx.doi.org/10.7554/eLife.92242 Text en © 2023, Posnien et al https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Developmental Biology
Posnien, Nico
Hunnekuhl, Vera S
Bucher, Gregor
Gene expression mapping of the neuroectoderm across phyla – conservation and divergence of early brain anlagen between insects and vertebrates
title Gene expression mapping of the neuroectoderm across phyla – conservation and divergence of early brain anlagen between insects and vertebrates
title_full Gene expression mapping of the neuroectoderm across phyla – conservation and divergence of early brain anlagen between insects and vertebrates
title_fullStr Gene expression mapping of the neuroectoderm across phyla – conservation and divergence of early brain anlagen between insects and vertebrates
title_full_unstemmed Gene expression mapping of the neuroectoderm across phyla – conservation and divergence of early brain anlagen between insects and vertebrates
title_short Gene expression mapping of the neuroectoderm across phyla – conservation and divergence of early brain anlagen between insects and vertebrates
title_sort gene expression mapping of the neuroectoderm across phyla – conservation and divergence of early brain anlagen between insects and vertebrates
topic Developmental Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522337/
https://www.ncbi.nlm.nih.gov/pubmed/37750868
http://dx.doi.org/10.7554/eLife.92242
work_keys_str_mv AT posniennico geneexpressionmappingoftheneuroectodermacrossphylaconservationanddivergenceofearlybrainanlagenbetweeninsectsandvertebrates
AT hunnekuhlveras geneexpressionmappingoftheneuroectodermacrossphylaconservationanddivergenceofearlybrainanlagenbetweeninsectsandvertebrates
AT buchergregor geneexpressionmappingoftheneuroectodermacrossphylaconservationanddivergenceofearlybrainanlagenbetweeninsectsandvertebrates