Development of a DNA damage-induced senescence model in osteoarthritic chondrocytes

Senescent cells (SnCs) have been described to accumulate in osteoarthritis (OA) joint tissues in response to injury, thereby participating in OA development and progression. However, clinical therapeutic approaches targeting SnCs using senolysis, although promising in preclinical OA models, have not...

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Detalles Bibliográficos
Autores principales: Georget, Mélina, Defois, Anaïs, Guiho, Romain, Bon, Nina, Allain, Sophie, Boyer, Cécile, Halgand, Boris, Waast, Denis, Grimandi, Gaël, Fouasson-Chailloux, Alban, Guicheux, Jérôme, Vinatier, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522398/
https://www.ncbi.nlm.nih.gov/pubmed/37659108
http://dx.doi.org/10.18632/aging.204881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522398/
https://www.ncbi.nlm.nih.gov/pubmed/37659108
http://dx.doi.org/10.18632/aging.204881

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