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Analytical sensitivity of a method is critical in detection of low-level BRCA1 constitutional epimutation
Recent reports based on a substantial number of cases, warrant need for population-based research to determine implications of constitutional methylation of tumor suppressor genes such as BRCA1 occurring in healthy tissue in the prediction of cancer. However, the detection of the constitutional meth...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522570/ https://www.ncbi.nlm.nih.gov/pubmed/37752189 http://dx.doi.org/10.1038/s41598-023-43276-7 |