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Dehydroascorbic acid sensitizes cancer cells to system x(c)(-) inhibition-induced ferroptosis by promoting lipid droplet peroxidation
Since the discovery of ferroptosis, it has been postulated that this type of cell death could be utilized in treatments for cancer. Unfortunately, several highly aggressive tumor models are resistant to the pharmacological induction of ferroptosis. However, with the use of combined therapies, it is...
Autores principales: | Ferrada, Luciano, Barahona, María José, Vera, Matías, Stockwell, Brent R., Nualart, Francisco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522586/ https://www.ncbi.nlm.nih.gov/pubmed/37752118 http://dx.doi.org/10.1038/s41419-023-06153-9 |
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