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Formulation development, in vivo bioequivalence and pediatric PBPK modeling studies of taste-masked ciprofloxacin chewable tablets

A taste-masked chewable tablet of ciprofloxacin using ion exchange resin Kyron T-134 for enhancing compliance for the paediatric population was developed. The drug-to-resin ratio was optimized for maximum taste masking by studying the effects of soaking time (X1) and mixing time (X2) on complexation...

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Detalles Bibliográficos
Autores principales:	Usmani, Muhammad Talha, Shoaib, Muhammad Harris, Siddiqui, Fahad, Ahmed, Farrukh Rafiq, Yousuf, Rabia Ismail, Saleem, Muhammad Talha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522605/ https://www.ncbi.nlm.nih.gov/pubmed/37752265 http://dx.doi.org/10.1038/s41598-023-43423-0

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