PPM1K mediates metabolic disorder of branched-chain amino acid and regulates cerebral ischemia-reperfusion injury by activating ferroptosis in neurons

Ischemic stroke is a neurological disorder caused by vascular stenosis or occlusion, accounting for approximately 87% of strokes. Clinically, the most effective therapy for ischemic stroke is vascular recanalization, which aims to rescue neurons undergoing ischemic insults. Although reperfusion ther...

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Detalles Bibliográficos
Autores principales: Li, Tao, Zhao, Lili, Li, Ye, Dang, Meijuan, Lu, Jialiang, Lu, Ziwei, Huang, Qiao, Yang, Yang, Feng, Yuxuan, Wang, Xiaoya, Jian, Yating, Wang, Heying, Guo, Yingying, Zhang, Lei, Jiang, Yu, Fan, Songhua, Wu, Shengxi, Fan, Hong, Kuang, Fang, Zhang, Guilian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522625/
https://www.ncbi.nlm.nih.gov/pubmed/37752100
http://dx.doi.org/10.1038/s41419-023-06135-x

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