Adjuvant mitotane versus surveillance in low-grade, localised adrenocortical carcinoma (ADIUVO): an international, multicentre, open-label, randomised, phase 3 trial and observational study

BACKGROUND: Adjuvant treatment with mitotane is commonly used after resection of adrenocortical carcinoma; however, treatment remains controversial, particularly if risk of recurrence is not high. We aimed to assess the efficacy and safety of adjuvant mitotane compared with surveillance alone follow...

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Detalles Bibliográficos
Autores principales: Terzolo, Massimo, Fassnacht, Martin, Perotti, Paola, Libé, Rossella, Kastelan, Darko, Lacroix, André, Arlt, Wiebke, Haak, Harm Reinout, Loli, Paola, Decoudier, Bénédicte, Lasolle, Helene, Quinkler, Marcus, Haissaguerre, Magalie, Chabre, Olivier, Caron, Philippe, Stigliano, Antonio, Giordano, Roberta, Zatelli, Maria Chiara, Bancos, Irina, Fragoso, Maria Candida Barisson Villares, Canu, Letizia, Luconi, Michaela, Puglisi, Soraya, Basile, Vittoria, Reimondo, Giuseppe, Kroiss, Matthias, Megerle, Felix, Hahner, Stefanie, Kimpel, Otilia, Dusek, Tina, Nölting, Svenja, Bourdeau, Isabelle, Chortis, Vasileios, Ettaieb, Madeleine Hester, Cosentini, Deborah, Grisanti, Salvatore, Baudin, Eric, Berchialla, Paola, Bovis, Francesca, Sormani, Maria Pia, Bruzzi, Paolo, Beuschlein, Felix, Bertherat, Jerome, Berruti, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Lancet, Diabetes & Endocrinology 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522778/
https://www.ncbi.nlm.nih.gov/pubmed/37619579
http://dx.doi.org/10.1016/S2213-8587(23)00193-6

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