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VNAR development through antigen immunization of Japanese topeshark (Hemitriakis japanica)
The VNAR (Variable New Antigen Receptor) is the smallest single-domain antibody derived from the variable domain of IgNAR of cartilaginous fishes. Despite its biomedical and diagnostic potential, research on VNAR has been limited due to the difficulties in obtaining and maintaining immune animals an...
Autores principales: | Takeda, Hiroyuki, Ozawa, Tatsuhiko, Zenke, Hiroki, Ohnuki, Yoh, Umeda, Yuri, Zhou, Wei, Tomoda, Honoka, Takechi, Akihiko, Narita, Kimiyoshi, Shimizu, Takaaki, Miyakawa, Takuya, Ito, Yuji, Sawasaki, Tatsuya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522858/ https://www.ncbi.nlm.nih.gov/pubmed/37771574 http://dx.doi.org/10.3389/fbioe.2023.1265582 |
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