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Occult myocardial injury is prevalent amongst elderly patients in the hospital-at-home setting. A retrospective analysis of 213 patients

BACKGROUND: Hospital-at-Home (HAH) is a valid alternative for in-hospital stay for a wide variety of clinical indications. Occult myocardial injury, associated with acute illness, mainly occurs in patients with a background of non-obstructive coronary disease. The aim of this study was to describe t...

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Autores principales: Marziano, Y., Abutbul, E., Sharabi, A., Grossbard, E., Berman, A., Kassif-Lerner, R., Barkai, G., Hakim, H., Segal, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522968/
https://www.ncbi.nlm.nih.gov/pubmed/37771606
http://dx.doi.org/10.1016/j.ijcrp.2023.200215
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author Marziano, Y.
Abutbul, E.
Sharabi, A.
Grossbard, E.
Berman, A.
Kassif-Lerner, R.
Barkai, G.
Hakim, H.
Segal, G.
author_facet Marziano, Y.
Abutbul, E.
Sharabi, A.
Grossbard, E.
Berman, A.
Kassif-Lerner, R.
Barkai, G.
Hakim, H.
Segal, G.
author_sort Marziano, Y.
collection PubMed
description BACKGROUND: Hospital-at-Home (HAH) is a valid alternative for in-hospital stay for a wide variety of clinical indications. Occult myocardial injury, associated with acute illness, mainly occurs in patients with a background of non-obstructive coronary disease. The aim of this study was to describe the prevalence of this phenomenon in our HAH population. METHODS: A retrospective description and analysis of data collected for patients admitted to the Sheba beyond's HAH services during 14 months. RESULTS: During a period of 14 months (7/10/21–6/12/22), blood troponin measurements were available for 213 patients (median age 78 years, 52% males) hospitalized mainly for infectious causes. The median HS (highly sensitive) troponin level was 7.7 ng/L (IQR = 13.2 ng/L) (the normal upper limit is 12 ng/L) with 31% of all patients demonstrating an abnormally increased troponin level (68/213). Of all patients, 64% had a background diagnosis of a cardiovascular disease (138/213), of whom, 49% had abnormal HS troponin levels (68/138). No patient suffered from acute cardiac function deterioration and no patient died during their hospital-at-home stay. CONCLUSION: The prevalence of occult myocardial injury amongst elderly patients admitted to hospital-at-home stay for diagnoses other than myocardial infarction is relatively high but it is not associated with worse short-term clinical outcomes.
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spelling pubmed-105229682023-09-28 Occult myocardial injury is prevalent amongst elderly patients in the hospital-at-home setting. A retrospective analysis of 213 patients Marziano, Y. Abutbul, E. Sharabi, A. Grossbard, E. Berman, A. Kassif-Lerner, R. Barkai, G. Hakim, H. Segal, G. Int J Cardiol Cardiovasc Risk Prev Research Paper BACKGROUND: Hospital-at-Home (HAH) is a valid alternative for in-hospital stay for a wide variety of clinical indications. Occult myocardial injury, associated with acute illness, mainly occurs in patients with a background of non-obstructive coronary disease. The aim of this study was to describe the prevalence of this phenomenon in our HAH population. METHODS: A retrospective description and analysis of data collected for patients admitted to the Sheba beyond's HAH services during 14 months. RESULTS: During a period of 14 months (7/10/21–6/12/22), blood troponin measurements were available for 213 patients (median age 78 years, 52% males) hospitalized mainly for infectious causes. The median HS (highly sensitive) troponin level was 7.7 ng/L (IQR = 13.2 ng/L) (the normal upper limit is 12 ng/L) with 31% of all patients demonstrating an abnormally increased troponin level (68/213). Of all patients, 64% had a background diagnosis of a cardiovascular disease (138/213), of whom, 49% had abnormal HS troponin levels (68/138). No patient suffered from acute cardiac function deterioration and no patient died during their hospital-at-home stay. CONCLUSION: The prevalence of occult myocardial injury amongst elderly patients admitted to hospital-at-home stay for diagnoses other than myocardial infarction is relatively high but it is not associated with worse short-term clinical outcomes. Elsevier 2023-09-23 /pmc/articles/PMC10522968/ /pubmed/37771606 http://dx.doi.org/10.1016/j.ijcrp.2023.200215 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Paper
Marziano, Y.
Abutbul, E.
Sharabi, A.
Grossbard, E.
Berman, A.
Kassif-Lerner, R.
Barkai, G.
Hakim, H.
Segal, G.
Occult myocardial injury is prevalent amongst elderly patients in the hospital-at-home setting. A retrospective analysis of 213 patients
title Occult myocardial injury is prevalent amongst elderly patients in the hospital-at-home setting. A retrospective analysis of 213 patients
title_full Occult myocardial injury is prevalent amongst elderly patients in the hospital-at-home setting. A retrospective analysis of 213 patients
title_fullStr Occult myocardial injury is prevalent amongst elderly patients in the hospital-at-home setting. A retrospective analysis of 213 patients
title_full_unstemmed Occult myocardial injury is prevalent amongst elderly patients in the hospital-at-home setting. A retrospective analysis of 213 patients
title_short Occult myocardial injury is prevalent amongst elderly patients in the hospital-at-home setting. A retrospective analysis of 213 patients
title_sort occult myocardial injury is prevalent amongst elderly patients in the hospital-at-home setting. a retrospective analysis of 213 patients
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522968/
https://www.ncbi.nlm.nih.gov/pubmed/37771606
http://dx.doi.org/10.1016/j.ijcrp.2023.200215
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