Preclinical assessment of a novel human antibody VH domain targeting mesothelin as an antibody-drug conjugate

Mesothelin (MSLN) has been a validated tumor-associated antigen target for several solid tumors for over a decade, making it an attractive option for therapeutic interventions. Novel antibodies with high affinity and better therapeutic properties are needed. In the current study, we have isolated an...

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Detalles Bibliográficos
Autores principales: Sun, Zehua, Chu, Xiaojie, Adams, Cynthia, Ilina, Tatiana V., Guerrero, Michel, Lin, Guowu, Chen, Chuan, Jelev, Dontcho, Ishima, Rieko, Li, Wei, Mellors, John W., Calero, Guillermo, Dimitrov, Dimiter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522976/
https://www.ncbi.nlm.nih.gov/pubmed/37771390
http://dx.doi.org/10.1016/j.omto.2023.09.002

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