Advances of nanotechnology for intracerebral hemorrhage therapy

Intracerebral hemorrhage (ICH), the most devastating subtype of stoke, is of high mortality at 5 years and even those survivors usually would suffer permanent disabilities. Fortunately, various preclinical active drugs have been approached in ICH, meanwhile, the therapeutic effects of these pharmace...

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Autores principales: Wang, Jiayan, Wang, Tianyou, Fang, Mei, Wang, Zexu, Xu, Wei, Teng, Bang, Yuan, Qijuan, Hu, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523393/
https://www.ncbi.nlm.nih.gov/pubmed/37771570
http://dx.doi.org/10.3389/fbioe.2023.1265153
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author Wang, Jiayan
Wang, Tianyou
Fang, Mei
Wang, Zexu
Xu, Wei
Teng, Bang
Yuan, Qijuan
Hu, Xin
author_facet Wang, Jiayan
Wang, Tianyou
Fang, Mei
Wang, Zexu
Xu, Wei
Teng, Bang
Yuan, Qijuan
Hu, Xin
author_sort Wang, Jiayan
collection PubMed
description Intracerebral hemorrhage (ICH), the most devastating subtype of stoke, is of high mortality at 5 years and even those survivors usually would suffer permanent disabilities. Fortunately, various preclinical active drugs have been approached in ICH, meanwhile, the therapeutic effects of these pharmaceutical ingredients could be fully boosted with the assistance of nanotechnology. In this review, besides the pathology of ICH, some ICH therapeutically available active drugs and their employed nanotechnologies, material functions, and therapeutic principles were comprehensively discussed hoping to provide novel and efficient strategies for ICH therapy in the future.
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spelling pubmed-105233932023-09-28 Advances of nanotechnology for intracerebral hemorrhage therapy Wang, Jiayan Wang, Tianyou Fang, Mei Wang, Zexu Xu, Wei Teng, Bang Yuan, Qijuan Hu, Xin Front Bioeng Biotechnol Bioengineering and Biotechnology Intracerebral hemorrhage (ICH), the most devastating subtype of stoke, is of high mortality at 5 years and even those survivors usually would suffer permanent disabilities. Fortunately, various preclinical active drugs have been approached in ICH, meanwhile, the therapeutic effects of these pharmaceutical ingredients could be fully boosted with the assistance of nanotechnology. In this review, besides the pathology of ICH, some ICH therapeutically available active drugs and their employed nanotechnologies, material functions, and therapeutic principles were comprehensively discussed hoping to provide novel and efficient strategies for ICH therapy in the future. Frontiers Media S.A. 2023-09-12 /pmc/articles/PMC10523393/ /pubmed/37771570 http://dx.doi.org/10.3389/fbioe.2023.1265153 Text en Copyright © 2023 Wang, Wang, Fang, Wang, Xu, Teng, Yuan and Hu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Wang, Jiayan
Wang, Tianyou
Fang, Mei
Wang, Zexu
Xu, Wei
Teng, Bang
Yuan, Qijuan
Hu, Xin
Advances of nanotechnology for intracerebral hemorrhage therapy
title Advances of nanotechnology for intracerebral hemorrhage therapy
title_full Advances of nanotechnology for intracerebral hemorrhage therapy
title_fullStr Advances of nanotechnology for intracerebral hemorrhage therapy
title_full_unstemmed Advances of nanotechnology for intracerebral hemorrhage therapy
title_short Advances of nanotechnology for intracerebral hemorrhage therapy
title_sort advances of nanotechnology for intracerebral hemorrhage therapy
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523393/
https://www.ncbi.nlm.nih.gov/pubmed/37771570
http://dx.doi.org/10.3389/fbioe.2023.1265153
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