Phenotypic features of genetically modified DMD-X(KO)X(WT) pigs

INTRODUCTION: Duchenne muscular dystrophy (DMD) is a hereditary neuromuscular disorder caused by mutation in the dystrophin gene (DMD) on the X chromosome. Female DMD carriers occasionally exhibit symptoms such as muscle weakness and heart failure. Here, we investigated the characteristics and repre...

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Detalles Bibliográficos
Autores principales: Okamoto, Kazutoshi, Matsunari, Hitomi, Nakano, Kazuaki, Umeyama, Kazuhiro, Hasegawa, Koki, Uchikura, Ayuko, Takayanagi, Shuko, Watanabe, Masahito, Ohgane, Jun, Stirm, Michael, Kurome, Mayuko, Klymiuk, Nikolai, Nagaya, Masaki, Wolf, Eckhard, Nagashima, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523442/
https://www.ncbi.nlm.nih.gov/pubmed/37772130
http://dx.doi.org/10.1016/j.reth.2023.09.010

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