Inducible CRISPR-targeted “knockdown” of human gut Bacteroides in gnotobiotic mice discloses glycan utilization strategies

Understanding how members of the human gut microbiota prioritize nutrient resources is one component of a larger effort to decipher the mechanisms defining microbial community robustness and resiliency in health and disease. This knowledge is foundational for development of microbiota-directed thera...

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Detalles Bibliográficos
Autores principales: Beller, Zachary W., Wesener, Darryl A., Seebeck, Timothy R., Guruge, Janaki L., Byrne, Alexandra E., Henrissat, Suzanne, Terrapon, Nicolas, Henrissat, Bernard, Rodionov, Dmitry A., Osterman, Andrei L., Suarez, Chris, Bacalzo, Nikita P., Chen, Ye, Couture, Garret, Lebrilla, Carlito B., Zhang, Zhigang, Eastlund, Erik R., McCann, Caitlin H., Davis, Gregory D., Gordon, Jeffrey I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523453/
https://www.ncbi.nlm.nih.gov/pubmed/37733741
http://dx.doi.org/10.1073/pnas.2311422120

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