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Structure of pre-miR-31 reveals an active role in Dicer–TRBP complex processing

As an essential posttranscriptional regulator of gene expression, microRNA (miRNA) levels must be strictly maintained. The biogenesis of many miRNAs is mediated by trans-acting protein partners through a variety of mechanisms, including remodeling of the RNA structure. miR-31 functions as an oncogen...

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Detalles Bibliográficos
Autores principales: Ma, Sicong, Kotar, Anita, Hall, Ian, Grote, Scott, Rouskin, Silvi, Keane, Sarah C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523476/
https://www.ncbi.nlm.nih.gov/pubmed/37725636
http://dx.doi.org/10.1073/pnas.2300527120

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