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Structure of pre-miR-31 reveals an active role in Dicer–TRBP complex processing
As an essential posttranscriptional regulator of gene expression, microRNA (miRNA) levels must be strictly maintained. The biogenesis of many miRNAs is mediated by trans-acting protein partners through a variety of mechanisms, including remodeling of the RNA structure. miR-31 functions as an oncogen...
Autores principales: | Ma, Sicong, Kotar, Anita, Hall, Ian, Grote, Scott, Rouskin, Silvi, Keane, Sarah C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523476/ https://www.ncbi.nlm.nih.gov/pubmed/37725636 http://dx.doi.org/10.1073/pnas.2300527120 |
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