LST-1 is a bifunctional regulator that feeds back on Notch-dependent transcription to regulate C. elegans germline stem cells

Notch signaling regulates stem cells across animal phylogeny. C. elegans Notch signaling activates transcription of two genes, lst-1 and sygl-1, that encode potent regulators of germline stem cells. The LST-1 protein regulates stem cells in two distinct ways: It promotes self-renewal posttranscripti...

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Detalles Bibliográficos
Autores principales: Ferdous, Ahlan S., Lynch, Tina R., Costa Dos Santos, Stephany J., Kapadia, Deep H., Crittenden, Sarah L., Kimble, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523584/
https://www.ncbi.nlm.nih.gov/pubmed/37729202
http://dx.doi.org/10.1073/pnas.2309964120

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