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A niche-mimicking polymer hydrogel-based approach to identify molecular targets for tackling human pancreatic cancer stem cells

BACKGROUND: Pancreatic adenocarcinoma (PAAD) is one of the most fatal human cancers, but effective therapies remain to be established. Cancer stem cells (CSCs) are highly resistant to anti-cancer drugs and a deeper understanding of their microenvironmental niche has been considered important to prov...

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Detalles Bibliográficos
Autores principales: Murota, Yoshitaka, Nagane, Mariko, Wu, Mei, Santra, Mithun, Venkateswaran, Seshasailam, Tanaka, Shinji, Bradley, Mark, Taga, Tetsuya, Tabu, Kouichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523636/
https://www.ncbi.nlm.nih.gov/pubmed/37759310
http://dx.doi.org/10.1186/s41232-023-00296-0