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A niche-mimicking polymer hydrogel-based approach to identify molecular targets for tackling human pancreatic cancer stem cells
BACKGROUND: Pancreatic adenocarcinoma (PAAD) is one of the most fatal human cancers, but effective therapies remain to be established. Cancer stem cells (CSCs) are highly resistant to anti-cancer drugs and a deeper understanding of their microenvironmental niche has been considered important to prov...
Autores principales: | Murota, Yoshitaka, Nagane, Mariko, Wu, Mei, Santra, Mithun, Venkateswaran, Seshasailam, Tanaka, Shinji, Bradley, Mark, Taga, Tetsuya, Tabu, Kouichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523636/ https://www.ncbi.nlm.nih.gov/pubmed/37759310 http://dx.doi.org/10.1186/s41232-023-00296-0 |
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