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Biochemical and histopathological evidence for beneficial effects of Empagliflozin pretreatment on acetic acid-induced colitis in rats

BACKGROUND: Ulcerative Colitis (UC) is a disorder which oxidative stress plays a critical role in its pathogenesis. Empagliflozin (EMPA) is a sodium-glucose cotransporter-2 (SGLT2) inhibitor that has been shown to have anti-inflammatory and antioxidative effects. The aim of this study was to investi...

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Detalles Bibliográficos
Autores principales: Nazari-Khanamiri, Fereshteh, Jafari, Abbas, Esmaeilzadeh, Zeinab, Ghasemnejad-Berenji, Morteza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523708/
https://www.ncbi.nlm.nih.gov/pubmed/37759154
http://dx.doi.org/10.1186/s12876-023-02958-2